Target Weed: Smooth & Large Crabgrass Host Turfgrass: St. Augustinegrass Safe Selective Matches: 2

How to Kill Smooth & Large Crabgrass in St. Augustinegrass Without Hurting Your Lawn

Direct Agronomic Answer

To selectively kill Smooth & Large Crabgrass in St. Augustinegrass without damaging your turf, apply Hi-Yield Atrazine Weed Killer (Atrazine 40.8%), Barricade 4FL (Prodiamine 65 WDG) (Prodiamine 40.7% (or 65% WDG)) when air temperatures are between 50°F and 85°F.

For early 1–3 leaf stages and mature 2–4 tiller plants, Quinclorac paired with a methylated seed oil (MSO) surfactant provides rapid systemic control within 7 to 14 days. In St. Augustine and Centipede lawns where Quinclorac causes severe chlorosis, Atrazine or Mesotrione (for Centipede only) must be used instead.

1. Labeled Safe Herbicides That Kill Smooth & Large Crabgrass in St. Augustinegrass

Recommended Product Active Ingredient & Group Application Temp (°F) Surfactant & Mixing Protocol Where to Buy
Hi-Yield Atrazine Weed Killer
EPA Reg. 34911-15-7401
Atrazine 40.8%
Group 5 (Photosystem II Inhibitor / Triazine)
50°F – 85°F
Rainfast: 6h
Do NOT add surfactant when spraying actively growing St. Augustine or Centipede above 80°F to avoid foliar yellowing. Irrigate lightly within 48 hours for root uptake. Check Price at DoMyOwn View on Amazon
Barricade 4FL (Prodiamine 65 WDG)
EPA Reg. 100-1139
Prodiamine 40.7% (or 65% WDG)
Group 3 (Microtubule Assembly Inhibitor / Dinitroaniline)
45°F – 90°F
Rainfast: 0h
Pre-emergent soil barrier: do NOT use foliar surfactant. Must be watered in with 0.5 inches of irrigation or rainfall within 14 days of application to activate. Check Price at DoMyOwn View on Amazon

2. What NOT to Spray on St. Augustinegrass When Treating Smooth & Large Crabgrass

Warning: Common Smooth & Large Crabgrass Killers That Damage St. Augustinegrass

Many retail herbicides advertised for Smooth & Large Crabgrass are formulated for different turf zones and will severely injure St. Augustinegrass:

  • AVOID Tenacity (Mesotrione 40%): Rated 'sod_production_only' on St. Augustinegrass — high risk of turf phytotoxicity or stunting.
  • AVOID Drive XLR8 (Quinclorac 18.92%): Rated 'avoid' on St. Augustinegrass — high risk of turf phytotoxicity or stunting.
  • AVOID Acclaim Extra (Fenoxaprop-p-ethyl 6.59%): Rated 'avoid' on St. Augustinegrass — high risk of turf phytotoxicity or stunting.
  • AVOID Pylex Herbicide (Topramezone 29.7%): Rated 'avoid' on St. Augustinegrass — high risk of turf phytotoxicity or stunting.

3. Optimal Seasonal Timing & Temperature Thresholds

Apply pre-emergent Prodiamine or Dithiopyr when 4-inch soil temperatures reach 50°F–55°F for three consecutive days, and spray post-emergent herbicides in late spring when seedlings have 2 to 3 leaves.

Post-emergent applications are most effective when Crabgrass is actively growing in moist soil and air temperatures remain below 85°F. Spraying mature multi-tiller plants in late August during drought stress significantly reduces herbicide translocation.

4. Diagnostic Checklist: Confirm It Is Smooth & Large Crabgrass Before Spraying

Not 100% sure? Use our AI Photo Weed Scanner or review the full Smooth & Large Crabgrass Botanical Profile.